Antimicrobial Applications of Engineered

Metal-Based Nanomaterials

27

Moondeep Chauhan, Gurpreet Kaur, Bunty Sharma,

and Ganga Ram Chaudhary

Abstract

Microbial resistance to the antibiotics is a serious problem at present and will

become alarming in near future. It is therefore important to establish a new

technology that has antibacterial potential without developing resistance against

bacterial strains. Nanotechnology has come to a way forward to address these

antimicrobial challenges. Metal-based engineered nanomaterials (ENMs) are the

main core of nanotechnology. Development in the field of metal-based ENMs has

shown the potential to use it as an antimicrobial agent. The current chapter will

critically evaluate the potential of metal-based ENMs as antimicrobial agents.

This will include their fabrication process, properties, interaction with bacteria,

and mode of action and mechanistic view of bacterial killing.

Keywords

Microbial resistance · Metal-based nanomaterials · Bacterial killing

M. Chauhan

SAIF/CIL, Panjab University, Chandigarh, India

G. Kaur · B. Sharma

Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University,

Chandigarh, India

G. R. Chaudhary (*)

Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University,

Chandigarh, India

SAIF/CIL, Panjab University, Chandigarh, India

e-mail: grc22@pu.ac.in

# The Author(s), under exclusive license to Springer Nature Singapore Pte

Ltd. 2022

R. C. Sobti, N. S. Dhalla (eds.), Biomedical Translational Research,

https://doi.org/10.1007/978-981-16-9232-1_27

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